Research Lines
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The research line in Photodynamic Systems develops technologies based on Photodynamic Therapy (PDT), aiming for greater efficacy and selectivity in the treatment of cancer and infections. The group employs nanocarriers such as liposomes, micelles, hybrid nanoparticles, and polyelectrolyte complexes to encapsulate photosensitizers, with the goal of enhancing solubility, stability, bioavailability, and release control. It also investigates the modulation of phototoxicity through formulation strategies, wavelength adjustment, and tumor microenvironment–responsive systems.
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The research line in Photodynamic Systems develops technologies based on Photodynamic Therapy (PDT), aiming for greater efficacy and selectivity in the treatment of cancer and infections. The group employs nanocarriers such as liposomes, micelles, hybrid nanoparticles, and polyelectrolyte complexes to encapsulate photosensitizers, with the goal of enhancing solubility, stability, bioavailability, and release control. It also investigates the modulation of phototoxicity through formulation strategies, wavelength adjustment, and tumor microenvironment–responsive systems.
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The Functional Materials research line investigates the synthesis, characterization, and application of nanomaterials with specific properties for biomedical and therapeutic purposes. The focus includes metallic nanoparticles, biocompatible polymers, stimulus-responsive hydrogels, and electrospun nanofibers for drug delivery or tissue regeneration. Research evaluates how structural and surface modifications influence stability, responsiveness, and cellular interaction, while also exploring hybrid systems that combine multiple functionalities. These materials are directly connected to the group’s other research lines, serving as carriers for drugs or photosensitizers, enhancing therapeutic efficacy, and reducing adverse effects.
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The Functional Materials research line investigates the synthesis, characterization, and application of nanomaterials with specific properties for biomedical and therapeutic purposes. The focus includes metallic nanoparticles, biocompatible polymers, stimulus-responsive hydrogels, and electrospun nanofibers for drug delivery or tissue regeneration. Research evaluates how structural and surface modifications influence stability, responsiveness, and cellular interaction, while also exploring hybrid systems that combine multiple functionalities. These materials are directly connected to the group’s other research lines, serving as carriers for drugs or photosensitizers, enhancing therapeutic efficacy, and reducing adverse effects.
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The Chemical Biology research line investigates the molecular mechanisms underlying the interaction between synthetic materials and biological systems, aiming to improve the delivery and activation of therapeutic agents. Studies include cellular internalization, selective cytotoxicity, reactive oxygen species generation, and light-induced cell death pathways, as well as active targeting strategies. This line provides the necessary biological validation to translate laboratory-developed systems into clinical applications, enabling more selective and personalized therapies.
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The Chemical Biology research line investigates the molecular mechanisms underlying the interaction between synthetic materials and biological systems, aiming to improve the delivery and activation of therapeutic agents. Studies include cellular internalization, selective cytotoxicity, reactive oxygen species generation, and light-induced cell death pathways, as well as active targeting strategies. This line provides the necessary biological validation to translate laboratory-developed systems into clinical applications, enabling more selective and personalized therapies.
